stem cells

Experiments Point to Possible Next-Gen Drug Therapies for Bipolar Disorder, Including for Lithium Non-Responders
Long-term use of mood-stabilizing drugs has long been a cornerstone of clinical treatment for bipolar disorder (BD). Lithium, which has been in use longer than any other, can be highly effective. In… Read More
Male-Female Differences in the Serotonin System May Help Explain Differences in Stress Vulnerability, Study Suggests
In recent years, a great deal of attention has been devoted by brain researchers to differences among the sexes in vulnerability to stress, and in turn, to the risk for disorders including anxiety… Read More
Lab-Grown Human Neurons Transplanted into the Rat Brain Grew, Connected, and Promise to Shed Light on Psychiatric Illness
During the last decade, neuroscientists have devised technologies that enable them to grow human brain cells under controlled conditions in the laboratory. A number of BBRF grantees and Scientific… Read More
Genome Engineering Combined with Stem Cell Technology Provide Insights on Disruptions in Brain Development
Twenty years ago, scientists first “spelled out” the full sequence of 3 billion pairs of DNA “letters” that make up the human genome. In the years since, they have discovered and validated many… Read More
Some Pathologies in Autism are Traced to Stem Cells in the Developing Brain
Evidence continues to mount that some and perhaps many of the biological abnormalities that underlie autism spectrum disorder (ASD) begin well before birth, as the brain’s cerebral cortex is… Read More