Substance Abuse

Large Genome Study Finds a ‘General Addiction Risk Factor’ Commonly Inherited Across Multiple Substance-Use Disorders
In recent years, studies involving large numbers of individuals have identified numerous locations in the human genome where commonly occurring variations in DNA sequence are associated with… Read More
Researchers Discover Potentially Targetable Brain Circuit Controlling Cocaine Withdrawal Anxiety and Relapse
In the past several decades, the field of addiction research has been revolutionized by new findings about the role of the neurotransmitter dopamine in affecting the brain’s reward pathways. For… Read More
A Circuit Causally Linked With Spontaneous Nicotine Addiction Remissions May Be a Powerful Addiction Treatment Target
By studying 129 people who were daily cigarette smokers and addicted to nicotine at the time they suffered brain damage, a team of researchers has identified a brain network that they believe is… Read More
Long-Term Regular Cannabis Users Showed Cognitive Deficits at Midlife in 45-Year Study
The question of whether cannabis use causes cognitive deficits or structural changes in the brain is still an open one, and has mostly been tested in adolescents and young adults. There is good… Read More
New Treatment Approach for Alcohol Use Disorder is Tested in Animals
A research team that included six BBRF grantees has reported encouraging results in animal-model tests exploring a potential new treatment for alcohol use disorder (AUD). Read More