Toward Brain-Based Prediction of Recovery: How Neuroimaging Can Help Combat the Substance-Use Epidemic
Tuesday, October 8, 2024, 2:00 pm EDT
Translation of research findings to the clinic remains a primary challenge of modern psychiatry. One way is via machine-learning approaches. When combined with network neuroscience, machine learning further allows for assessment of systems-level brain processes in an unbiased manner. This talk will present recent work demonstrating the utility of this approach to identify specific brain networks that predict individual differences in complex addiction outcomes, including opioid and cocaine use-risk in adults and alcohol use-risk in youth. Recommendations for future work using machine learning models in psychiatry, and within the specific context of the current addiction epidemic, will be discussed.
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Dr. Yip is an Associate Professor of Psychiatry at Yale School of Medicine and the Director of the Yale Imaging and Psychopharmacology (YIP) Lab. Her lab uses neuropsychiatric research methods to identify biological mechanisms of mood disorders, addictions, and their treatments. This work has received competitive funding from the National Institute of Health (NIH), the UK’s Medical Research Council (MRC), the Canadian Institute of Health Research (CIHR), the Brain and Behavior Research (BBR) Foundation and the National Center on Addiction and Substance Abuse. Ongoing work uses advanced neuroimaging analysis methods to assess large-scale systems dynamics within the context of addictions and their treatments. This includes application of machine learning approaches to identify predictive neuromarkers of complex clinical outcomes in adults, and of clinical risk in youth. She received her BA in Psychology from New York University and her PhD in Psychiatry from the University of Oxford.
Jeffrey Borenstein, M.D., serves as the President & CEO of the Brain & Behavior Research Foundation, the largest private funder of mental health research grants. Dr. Borenstein developed the Emmy-nominated public television program “Healthy Minds,” and serves as host and executive producer of the series. The program, broadcast nationwide, is available online, and focuses on topics in psychiatry in order to educate the public, reduce stigma and offer a message of hope. Dr. Borenstein served as Editor-in-Chief of Psychiatric News, the newspaper of the American Psychiatric Association from 2012 - 2023.
Dr. Borenstein is a Fellow of the New York Academy of Medicine and serves as the Chair of the Section of Psychiatry at the Academy. He also has served as the President of the New York State Psychiatric Association. Dr. Borenstein earned his undergraduate degree at Harvard and his medical degree at New York University.